Page 51 - Inaugural Lecture Prof Dr Ahmad Sobri Muda

Ahmad Sobri Muda

Figure 16 LVO n a 71-year-old lady, in which MERCI device deployed
at M1 portion of the right MCA.

Collaterals in Stroke

Collaterals result from development of fundamentally important
alternatives when the main arteries supplying the brain are blocked.
This phenomenon is crucial alternative for restoring blood flow
to ischemic areas. Good collateral circulation has been shown to
result in a better functional outcome and a lower risk of recurrence
in stroke patients with various etiologies or those undergoing
endovascular or pharmacological treatment. The status of collateral
in acute ischemic stroke patients differs. Even after 4.5 hours,
patients with adequate collateral circulation are likely to have
a superior clinical outcome with intra-arterial revascularisation
treatment. Collaterals are primarily formed as a result of inadequate
blood supply during an acute ischemic stroke. To avoid hypoxia,
efficient core reperfusion to the ischemic area is accomplished by
using a net overall flow that incorporates residual anterograde flow

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